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    Research Associate/Senior Research Associate - Adme

    O2h
    2-4 years
    Not Disclosed
    Ahmedabad
    10 June 28, 2024
    Job Description
    Job Type: Full Time Education: B.Sc./ M.Sc./ M.Pharm/ B.Pharm/ Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

    Job Description

    Reporting and Team Collaboration

    • Report to the senior team leader.
    • Work with a group of in vitro assay biologists.
    • Learn and coach group members to improve skills and productivity.
    • Conduct day-to-day testing and profiling of compounds in cells/protein-based assays or experiments in a team-oriented environment.
    • Analyze, interpret, draw conclusions, and test new methodologies.
    • Multitask, recognize problems, provide input to solutions, draft reports, and properly document experiments.
    • Present results proficiently within the lab, at project or review meetings, and for other internal/external parties as needed.

    Assay Development and Data Analysis

    • Perform all ADME assays.
    • Develop methods and collect data using LC-MS/MS and other modalities (absorbance/fluorescence).
    • Develop new assays for ADME activities.
    • Analyze data from enzyme activities using GraphPad Prism and MS Excel.
    • Analyze MS data using Sciex.

    Report Compilation and Collaboration

    • Compile reports and interface with collaborators and clients.
    • Coordinate with third-party collaborators for PK studies (animal models).

    General Lab Contributions

    • Contribute to group activities such as ordering, stocking, and follow-up.
    • Take responsibility for ordering lab supplies and keeping the lab stocked and in good order.
    • Work closely with other biology groups involved in screening, cell biology, protein biology, and ADME.
    • Offer integrated drug discovery support alongside chemistry for multiple client-based projects.

    Job Requirements

    Experience and Skills

    • Minimum 2-4 years of working experience with LC-MS/MS, HPLC, bio-analytical studies, etc.
    • Hands-on/practical exposure to general biotech laboratory equipment (cell-culture lab, in-vitro and ADME lab).
    • Theoretical understanding and practical work experience with:
      • Cell culture techniques (established cell lines).
      • ADME assays (microsomal stability, plasma stability, solubility, permeability, CYP inhibition assays, plasma protein binding assays, etc.).
    • High self-motivation to initiate projects and work independently under aggressive deadlines.
    • Strong technical knowledge with exceptional attention to detail.
    • Excellent understanding and knowledge of laboratory tools, techniques, methods, and underlying principles.

    Personal Qualities and Interpersonal Skills

    • Ability to overcome technical challenges and exercise sound judgment under pressure.
    • Excellent personal rapport and ability to engender trust and respect.
    • Ability to work well as part of a small focused team and build relationships.
    • Exceptional communication skills and ease in interaction with all stakeholders.
    • Infectious enthusiasm for life, work, and making a difference in the world.
    • Bright, friendly, and flexible personality with agility to switch between different skill sets.
    • Exceptional organizational skills that thrive in a fast-paced and vibrant team environment.
    • Positivity, focus, and a winning mentality allied with kindness.
    • Curiosity, energy, creativity, and bravery with a strong desire to help build the o2h culture.

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