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Senior Scientist, Protein Chemistry

2+ years
Not Disclosed
10 Nov. 13, 2024
Job Description
Job Type: Full Time Education: B.Sc./ M.Sc./ M.Pharm/ B.Pharm/ Life Sciences Skills: Causality Assessment, Clinical SAS Programming, Communication Skills, CPC Certified, GCP guidelines, ICD-10 CM Codes, CPT-Codes, HCPCS Codes, ICD-10 CM, CPT, HCPCS Coding, ICH guidelines, ICSR Case Processing, Interpersonal Skill, Labelling Assessment, MedDRA Coding, Medical Billing, Medical Coding, Medical Terminology, Narrative Writing, Research & Development, Technical Skill, Triage of ICSRs, WHO DD Coding

Why Patients Need You

Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, you will apply cutting-edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.

What You Will Achieve

The Antibody Engineering group is seeking an energetic, highly motivated, and creative Senior Scientist with a strong background in chemical biology, protein chemistry, and/or protein engineering to join Pfizer Oncology’s antibody-drug conjugate (ADC) discovery research team. You will conceive novel ADC and/or targeted therapy technology platforms and work collaboratively with cancer biologists, immunologists, and translational scientists to advance these ideas into drug candidates. The successful candidate will perform hands-on experiments to produce novel ADCs and generate preclinical data, think strategically about advancing projects, and drive projects to clear go/no-go decision points.

How You Will Achieve It

  • Conceptualize novel drug linker, bioconjugate, or protein engineering technology opportunities for therapeutic development (ADC or otherwise).
  • Actively design and execute comprehensive experimental plans consisting of in vitro and in vivo experiments that inform and enable project progression.
  • Work independently and contribute to projects outside of your own expertise.
  • Effectively communicate and collaborate across a diverse research department to advance preclinical projects.
  • Present data at research project team meetings and seminars to drive recommendations for drug discovery and/or development decisions.
  • Lead programs by executing lead optimization strategies and driving discovery goals.
  • Prepare patent applications and publish impactful research.
  • Expand the capabilities of the Antibody Engineering group by implementing new techniques and cutting-edge technologies.

Qualifications

Must-Have:

  • Ph.D. in Chemistry, Biochemistry, Chemical Biology, or a related discipline, OR
  • M.S. degree in Chemistry, Biochemistry, Chemical Biology, or related discipline with a minimum of 7 years of experience, with 3 years in the biopharmaceutical industry, OR
  • B.S. degree in Chemistry, Biochemistry, Chemical Biology, or related discipline with a minimum of 9 years of experience, with 5 years in the biopharmaceutical industry.
  • Contemporary knowledge of chemical, protein engineering, and/or bioconjugation concepts and design tools required for biopharmaceutical drug discovery.
  • Excellent oral and written communication skills.

Nice-to-Have:

  • Track record of accomplishment in the biopharmaceutical industry with high-impact publications from scientific work to date.
  • Experience working in matrix teams to deliver defined objectives.

Physical/Mental Requirements

  • Ability to lift 10 lbs.
  • Relocation support available.

Compensation and Benefits

  • Annual base salary ranging from $88,300.00 to $147,100.00, with eligibility for Pfizer’s Global Performance Plan bonus target of 12.5% of the base salary.
  • Comprehensive and generous benefits package, including a 401(k) plan with Pfizer Matching Contributions, paid vacation, holiday, personal days, paid caregiver/parental leave, and medical, prescription drug, dental, and vision coverage.
  • Relocation assistance may be available based on business needs and/or eligibility.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates. This position requires permanent work authorization in the United States. Pfizer is an E-Verify employer.